Renoprotective effect of Eryngium caucasicum in Gentamicin-induced nephrotoxic mice
نویسندگان
چکیده
منابع مشابه
Renoprotective Effect of Eryngium Caucasicum in Gentamicin-induced Nephrotoxic Mice
Recent studies show that hydrogen peroxide free radicals have an important role in the renal damage induced by Gentamicin. Previously we studied the hydrogen peroxide scavenging activity of Eryngium caucasicum. This work was conducted to evaluate the possible renoprotective effect of Eryngium caucasicum against Gentamicin-induced renotoxicity. Extracts at the doses 200 and 400 mg/kg/day for 10 ...
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Gentamicin is an important aminoglycoside antibiotic. However its use is limited to serious and life threatening gram negative infections, because of its high nephrotoxicity potential in patients. There are reports that safranal, the active ingredient of saffron with antioxidant properties, exerts protective effect against ischemic injuries occurred by certain nephrotoxins including gentamicin....
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Objective(s): Gentamicin is used for the treatment of Gram-negative bacterial infections. However, gentamicin administration is limited because of nephrotoxicity. The aim of the present study was to evaluate the protective effect of crocin against gentamicin-induced nephrotoxicity in rats. Materials and Methods: Thirty two male Wistar rats received gentamicin (100 mg/kg, IP), with or without c...
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Objective(s):Gentamicin sulphate (GS) nephrotoxicity seems to be related to the generation of reactive oxygen species. There is evidence that oxygen preconditioning increases the activity of antioxidant enzymes. Materials and Methods: Forty eight female rats were divided into 6 groups (n=8) as follows: group 1 was the control, group 2 received daily GS, groups 3,4 and 5 received oxygen 2 hr/day...
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ژورنال
عنوان ژورنال: Arhiv za bioloske nauke
سال: 2011
ISSN: 0354-4664,1821-4339
DOI: 10.2298/abs1101157e